Alex Cuthbert's try helped secure Wales the Grand Slam but they were made to sweat all the way by a determined France side in their 16-9 RBS 6 Nations victory.
Giovanbattista Venditti's try just after halftime gave Italy their maiden win under coach Jacques Brunel and condemned Scotland to a 13-6 defeat and a first Wooden Spoon since 2007.
Interim boss Stuart Lancaster put down a sizeable marker for why he should be England's next full-time coach after his side upset an experienced French team 24-22 in Paris.
Second-half tries from Jamie Roberts and Alex Cuthbert helped Wales see off a resolute Italy side 24-3 to keep their RBS 6 Nations Grand Slam dreams alive.
Stand-in skipper Rory Best celebrated his temporary appointment in perfect style by crossing for one of Ireland's four scores in their 32-14 win as they condemned Scotland to a fourth consecutive RBS 6 Nations defeat.
Tommy Bowe's first-half double was in vain as France denied Ireland a first win in Paris for 12 years as they came back to draw 17-17 at Stade de France.
France continued their winning start to the RBS 6 Nations but were given an almighty scare by Scotland at Murrayfield before running out 23-17 winners.